Skin Atlas

Management of Nodules

Subcutaneous nodules can be minimized by rotating infusion sites frequently and avoiding reuse of previously affected areas.
If nodules form, gentle massage (by hand or using a spiky rubber massage ball) may assist in resolution.
- Local massage should proceed slowly and be stopped if discomfort becomes too intense.*
- If tolerated, massage can be continued for at least a few days after the needle is withdrawn.*
Persistent or painful nodules may require medical evaluation.

Preventing Nodules

Expert insights video
Alexis Truax, RN
Debra Johnston, RN

Nodule Management

Expert insights video
Lynne H. Robertson, Dermatologist
Debra Johnston, RN

*Expert Opinion, Dr. Marc-André Doré, August 2023.